Sign In | Join Free | My autoplansearch.com
autoplansearch.com
Products
Search by Category
Wholesale Marketplace
Home > Dyestuffs >

Antineoplastic Lyophilized Powder Injection / Daunorubicin Hydrochloride Injection 20mg Anti cancer

Categories Lyophilized Powder Injection
Brand Name: Newlystar
Place of Origin: China
MOQ: 10000 vials
Payment Terms: L/C, T/T
Delivery Time: 45days
Packaging Details: 10 vials/box
Model Number: Lyophilized, 20mg
Certification: GMP
Price: Negotiation
Supply Ability: 50, 000 vials per day
Product: Daunorubicin Hydrochloride for Injection
Specification: Lyophilized, 20mg
Standard: BP, USP
Packing: 10 vials/box
  • Haven't found right suppliers
  • Our buyer assistants can help you find the most suitable, 100% reliable suppliers from China.
  • And this service is free of charge.
  • we have buyer assistants who speak English, French, Spanish......and we are ready to help you anytime!
  • Submit Buying Request
    • Product Details
    • Company Profile

    Antineoplastic Lyophilized Powder Injection / Daunorubicin Hydrochloride Injection 20mg Anti cancer

    Antineoplastic Lyophilized Powder Injection / Daunorubicin Hydrochloride Injection 20mg Anti cancer


    Product : Daunorubicin Hydrochloride for Injection

    Specification : Lyophilized, 20mg

    Standard : BP, USP

    Packing : 10 vials/box


    Description :

    Doxorubicin Hydrochloride for Injection, is a sterile red-orange lyophilized powder for intravenous use only, is available in 10, 20 and 50 mg single dose vials.


    Indication and dosage :

    For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.


    To treat acute lymphocytic leukemia

    45 mg/m2 daily for first 3 days of a 32-day course of vincristine, prednisone, and asparaginase combination therapy


    To treat acute nonlymphocytic leukemia

    45 mg/m2 daily for first 3 days of first course of cytarabine combination therapy and first 2 days of second course of cytarabine combination therapy


    Pharmacodynamics :

    Daunorubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Daunorubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Daunorubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.


    Mechanism of action

    Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

    Quality Antineoplastic Lyophilized Powder Injection / Daunorubicin Hydrochloride Injection 20mg Anti cancer wholesale
    Send your message to this supplier
     
    From:
    Enter your email please.
    To: Newlystar (Ningbo) Medtech Co.,Ltd.
    Subject:
    Message:
    Characters Remaining: (0/3000)
     
    Inquiry Cart 0

    Home| Products| Suppliers| Quality Suppliers| Site Map |About Us |Contact Us |Help |关于我们 |联系我们

    Copyright © 2009 - 2017 autoplansearch.com. All rights reserved.